TY - JOUR AU - Laiq, Nasreen AU - Khan, Muhammad Naseem AU - Khan, Shahid AU - Reddy, CVM PY - 2011/08/12 Y2 - 2024/03/28 TI - INDUCTION AND EMERGENCE CHARACTERISTICS OF PROPOFOL IN TWO DIFFERENT CONCENTRATIONS IN DAY CASE EYE SURGERY IN CHILDREN JF - Journal of Postgraduate Medical Institute JA - J Postgrad Med Inst VL - 21 IS - 3 SE - Original Article DO - UR - https://jpmi.org.pk/index.php/jpmi/article/view/189 SP - AB - <span style="font-family: Times New Roman; color: #1f1a17; font-size: x-small;"><span style="font-family: Times New Roman; color: #1f1a17; font-size: x-small;"><span style="font-family: Times New Roman; color: #1f1a17; font-size: x-small;"><p>Objective: To compare the induction characteristics of two different concentrations of propofol i.e. 1%</p><p>and 2% in children undergoing eye surgeries.</p><p>Material and Methods: In this cross-sectional comparative study 100 consecutive patients of ASA</p><p>status 1 and II coming for elective eye surgeries were divided into two groups of 50 each. Group A were</p><p>given propofol 1% while patients in Group B were given propofol 2% for induction of anaesthesia and</p><p>were maintained with 1% isoflurane and 60% nitrous oxide in oxygen. Induction characteristics i.e. loss of</p><p>consciousness or onset time of anaesthesia, pain on injection, spontaneous or purposeless movements,</p><p>spasm just after intubation and conditions of intubation were assessed and compared in two groups.</p><p>Student't test and chi- square test were applied.</p><p>Results: Loss of consciousness was more rapid with propofol 2% compared with propofol 1% (40s Vs</p><p>48s; P = 0.02). Pain on injection occurred in 5(10%) and 10 (20%) patients (P = 0.09) after propofol 1%</p><p>and 2% respectively. Spontaneous movements during induction occurred in 8 (16%) and 12 (24%) patients</p><p>(P=0.18); satisfactory intubation was done in 40 (80%) and 45 (90%) patients (P=0.19), while spasm just</p><p>after intubation was noticed in 1 ( 2%) and 3 patients (6% ), receiving propofol 1% and 2% respectively.</p><p>Haemodynamic changes were not different in the two groups.</p><p>Conclusion: Propofol 1% and propofol 2% are equally effective and safe for induction of anaesthesia in</p><p>children undergoing eye surgeries.</p></span></span></span> ER -