TY - JOUR AU - Khan, Atta Muhammad AU - Ali, Zafar AU - Salahuddin, Ghazi Sultan AU - ., Nowsherwan AU - Kamal, Musharaf AU - Asghar, Muhammad AU - Abdur Rahman Afridi, Muhammad PY - 2020/08/27 Y2 - 2024/03/28 TI - UROPATHOGEN ISOLATES AND THEIR ANTIBIOTIC SENSITIVITY IN PATIENTS WITH INDWELLING CATHETER ASSOCIATED URINARY TRACT INFECTIONS JF - Journal of Postgraduate Medical Institute JA - J Postgrad Med Inst VL - 34 IS - 1 SE - Original Article DO - UR - https://jpmi.org.pk/index.php/jpmi/article/view/2641 SP - AB - <p class="p1">Objective: To determine the frequency of uropathogen isolates and their antibiotic sensitivity against commonly prescribed antibiotics in patients having indwelling catheter associated UTIs (CAUTIs) at our institution.</p><p class="p1">Methodology: Our study was carried out at the Departments of Internal Medicine and Nephrology, Lady Reading Hospital (LRH), Peshawar, from July 2018 to December 2018. It was a descriptive cross sectional study. Patients of both genders with UTI and who were catheterized with age ranging from 16 to 65 years were included through consecutive (non-probability) sampling technique. Specimens (catheter tip) were obtained under strict aseptic techniques to detect common bacterial isolates and their sensitivities against commonly prescribed antibiotics. Data were analyzed via SSPS (version 20).</p><p class="p1">Results: There were total 179<span class="Apple-converted-space">  </span>catheterized patients. Among them, 67% patients were female. Mean age was 47 ±2.15 years. Sixty six (37%) patients had catheter associated UTI and among them 42 (63.64%) patients were female. Escherichia coli was found in 37% patients followed by Klebsiella pneumoniae in 20% patients. Resistance to the commonly used antibiotics included amoxicillin-clavulanate (97%), quinolones (93%), ceftriaxone (86%), cefoperazone-sulbactam (12%), piperacillin-tazobactum (11%) and meropenem (11%).<span class="Apple-converted-space"> </span></p><p class="p1">Conclusion: In our setup, the frequency of catheter associated urinary tract infection was 37% and the most frequent bacteria found was <em>Escherichia coli </em>(37%) followed by <em>Klebsiella pneumoniae</em> (20%). A higher resistance was found to the commonly prescribed antibiotics.</p> ER -