TY - JOUR AU - Saeedi, Muhammad Ilyas AU - Khan, Muhammad Ali AU - Shah, S. Musanif AU - Rehman, Masood ur AU - Ahmad, Mushtaq AU - Zubair, Tariq PY - 2011/08/28 Y2 - 2024/03/29 TI - Peflacin (Pefloxacin) in the treatment of Typhoid Fever JF - Journal of Postgraduate Medical Institute JA - J Postgrad Med Inst VL - 9 IS - 1 SE - Original Article DO - UR - https://jpmi.org.pk/index.php/jpmi/article/view/487 SP - AB - Twenty Five patients (mean age of 23.9 years) with clinical diagnosis of typhoid fever supported with positive widal test and / or blood / bone marrow culture were included in the trial. Most of the patient had already used Chloramphenicol and Amoxycillin without any effect. Peflacin (Pefloxacin) was administered orally to all patients at a daily dose of 800mg (400 mg B.D) for seven days. Clinical cure was achieved in all patients and 90% of them were apyrexial on the 4<sup>th</sup> day of treatment. They remained apyrexial for 4 weeks after completion of treatment. Patient compliance was god and well tolerated the drug. ER -