ASSOCIATION OF IRON DEFICIENCY ANAEMIA WITH FEBRILE FITS

Main Article Content

Muhammad Awais
Asma Razzaq
Saad Ateeq
Hakeem Ullah

Abstract

Objective: To determine association of iron deficiency anemia with febrile fits among children between 6 months to 59 months.


Methodology: This case-control study was conducted at BLINDED from 1st January 2021 to 31st December 2021. The study enrolled the sample via non-probability convenience sampling. A total of 190 sample was enrolled in this study with 95 as cases and 95 as controls. The cases were defined as the patients of either gender who were admitted to pediatric unit with diagnosis of 1st episode febrile fits; while the controls were defined to be patients of either gender who were admitted to pediatric unit with fever but without fits. Blood sample was collected for laboratory investigations and a pre-designed performa was used to extract the data. Data was analyzed using SPSS v.25.0, wherein descriptive and analytical statistics were applied where needed.


Results: The mean age of the sample was 3.54±2.115 years (cases: 2.76±1.44 years & controls: 4.31±2.384 years). In gender distribution, 116 (61.1%) were males and 74 (38.9%) were females. In temperature statistics, a mean of 102.771±1.4278oF was recorded in all the patients (cases: 102.879±1.43oF, controls: 102.662±1.422oF). In total, 31 (16.3%) patients were diagnosed to be Iron Deficiency Anaemia [cases: 18/95 (18.9%), control: 13/95 (13.7%)] with an Odds Ratio of 1.475 with increased likelihood of Iron Deficiency Anaemia in cases as compared to controls (p-value: 0.326).


Conclusion: The study concluded an insignificant association but a slightly positive likelihood of febrile fits with Iron Deficiency Anaemia.

Article Details

How to Cite
1.
Awais M, Asma Razzaq, Saad Ateeq, Hakeem Ullah. ASSOCIATION OF IRON DEFICIENCY ANAEMIA WITH FEBRILE FITS. J Postgrad Med Inst [Internet]. 2022 Aug. 19 [cited 2022 Oct. 7];36(3):162-5. Available from: https://jpmi.org.pk/index.php/jpmi/article/view/3079
Section
Original Article

References

Kwak BO, Kim K, Kim SN, Lee R. Re¬lationship between iron deficiency anemia and febrile seizure in children: A systematic review and meta-anal¬ysis. Seizure. 2017;52:27-34. DOI: 10.1016/j.seizure.2017.09.009.

Dalbem JS, Siqueira HH, Espinosa MM, Alvarenga RP. Febrile seizures: a pop¬ulation-based study. J Pediatr (Rio J). 2015;91(6):529-34. DOI: 10.1016/j. jped.2015.01.005.

Hussain S, Tarar SH, Moin Ud Din Sabir. Febrile seizures: demographic, clini¬cal and etiological profile of children admitted with febrile seizures in a ter¬tiary care hospital. J Pak Med Assoc. 2015;65(9):1008-10.

Habib Z, Akram S, Ibrahim S, Hassan B. Febrile seizures: Factors affecting risk of recurrence in Pakistani children pre¬senting at The Aga Khan University Hos¬pital. J Pak Med Assoc. 2003;53:11-7.

Rehman N, Billoo AG. Association be¬tween iron deficiency anemia and fe¬brile seizures. J Coll Physicians Surg Pak. 2005;15:338-40.

De Zárate MM, Del Castillo JG, Jiménez AJ, Salmerón PP, Roca FL, Tey JG, BOR¬RÁS MR, Grinspan MR, LAMBERECHTS EJ, Esparza CI, MIR10 MM. Study IN¬FURG-SEMES: epidemiology of infec¬tions treated in hospital emergency services and evolution during the last decade. Emergencias. 2013;25:368- 78.

Mohebbi MR, Holden KR, Butler IJ. FIRST: A practical approach to the caus¬es and management of febrile seizures. J Child Neurol. 2008;23(12):1484-8. DOI: 10.1177/0883073808319317.

Graves RC, Oehler K, Tingle LE. Fe¬brile seizures: risks, evaluation, and prognosis. Am Fam Physician. 2012;85(2):149-53.

Sultan T, Hanif AI , Ali S. Iron deficiency anemia as a risk factor for simple fe¬brile seizures. Pak J Neurological Sci. 2017;12(3):36-40.

Haemoglobin concentrations for the di¬agnosis of anaemia and assessment of severity. Who.int. [cited 2022 February 2]. Available from URL: https://www. who.int/vmnis/indicators/haemoglobin. pdf.

Iron Deficiency Anaemia; Assessment, Prevention, and Control: A guide for program managers 2001. [cited 2022 February 2]. Available from URL: https:// www.who.int/nutrition/publications/en/ ida_assessment_prevention_control. pdf.

Lal V, Kumar H, Hanif S, Parkash O, Arwani S. Association of iron defi¬ciency anemia in children with febrile convulsions. Pak J Neurological Sci. 2016;11(3):2-8.

Khan SA, Salahuddin A, Noman MA. Association between iron deficiency anemia and febrile seizures. J Postgrad Med Inst. 2016;30(4):352-5.

Khan SA, Khan J, Gul MS, Akbar K, Far¬id A, Adnan M. Iron deficiency associat¬ed with febrile seizures. Rawal Med J. 2021;46(3):530-32.

Sultan T, Hanif AI, Ali S. Iron deficiency anemia as a risk factor for simple fe¬brile seizures. Pak J Neurological Sci. 2017;12(3):36-40.

Habibian N, Alipour A, Rezaianzadeh A. Association between iron deficiency anemia and febrile convulsion in 3- to 60-month-old children: A systematic review and meta-analysis. Iran J Med Sci. 2014;39(6):496-505.