Cholesterol and Lipids in Cancer Patients

Abstract

Fifty biopsy proven cancer cases were studied after excluding liver and kidney disorders for changes in lipids metabolism with special reference to fasting serum Triglycerides (TG). Total Lipids, cholesterol, High dentsity Lipoprotein-Cholesterol (HDLc) and Low Density Lipoprotein-Cholesterol (LDLc). Significant changes were observed. Comparing different groups of cancer patients Vs controls, TG level was 157 + 19.03 and 204.86 + 23.41 mg/dl (P< 0.05), cholesterol was 172.92 + 6.54 and 213.86 + 9.87mg/dl (P<0.01) HDLc was 32.17 + 1.41 and 38.2 +1.65, LDLc was 113.6 + 55.62 and 134.7 + 7.85 mg/dl (p<0.05), respectively. TG and Cholesterol levels were below the normal control levels in 78% and 54% of the cases respectively. In 56% of cases total lipid level waws within the normal control level while in 28% of the cases it was below the noraml range. HDLc and LDLc levels were below the normal control level in 62% and 70% of the cases respectively. low level of cholesterol and TG were estimated in patients with maligncies of different organs. However cause and effect relationship could not be established.