Ophthalmic Manifestation of Graves Disease

Abstract

The purpose of this study is to find out various ophthalmic sign in patients with Graves' disease, their relative frequency and the percentage of patietns severely affected resulting in loss of vision. This prospective study is based on finding ophthalmic signs in one hundred patients with established Graves' disease attending ophthalmic and medical units of KTH, Peshawar as well as Institute of Radiotherapy and Nuclear medicine (IRNUM) Peshawar. the total duration of study is seventeen months i.e. from August 1994 to December 1995. For study, a proforma has been setup giving all the possible ophthalmic sign which may be present in patients with Graves' disease. Patient's name, age, sex and address were recorded. The proforma also gives information about the mode of presentation that how and when the patients with Graves' disease seek medical advice. The age sex distribution of Graves' disease and the percentage of patient with positive family history and smoking history are also sorted out. Relation of thyroid hormone level to severity of ophthalmic signs and percentage of euthyroid patients with ophthalmopathy is also taken into consideration. Moreover unilateral and bilateral presentation is also compared.