MRI brain findings in patients with high serum prolactin levels
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Abstract
Objective: The purpose of the study was to find MRI findings in patients with Prolactin levels above1000mIU/L.
Methodology: This Retrospective study was conducted in Radiology Department, Rehman Medical Institute,Peshawar, from December 2009 to October 2012. A total of 86 patients, aged 16-48 years with high Prolactinlevels, were screened with MRI for pituitary gland abnormalities. Only new undiagnosed patientswere considered for the study. Children and patients with known causes for hyperprolactinaemia wereexcluded.
Results: The most common abnormality on MRI was microadenoma (n=34, 39.5%) followed by macroadenoma(n=14, 16.3%). 12(7%) cases of complete/partial empty sella syndrome were seen. Macroadenomawas more common in males (n=6 out of 14, 42.3%) while microadenoma was more common in females(n=32 out of 72, 44.4%).
Conclusion: Majority of Patients had an abnormal MRI finding, showing that MRI screening should berecommended for Prolactin levels above 1000mIU/L. Microadenoma was the most common abnormality,having higher incidence in female patients.
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