MRI brain findings in patients with high serum prolactin levels

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Seema Gul
Mohammad Naeem
Muhammad Zia-ul-Islam Khan
Muhammad Adil
Syed Hussain Abbas
Ayasha Khan
Syeda Maria Naz
Muhammad Usman Khan

Abstract

Objective: The purpose of the study was to find MRI findings in patients with Prolactin levels above1000mIU/L.

Methodology: This Retrospective study was conducted in Radiology Department, Rehman Medical Institute,Peshawar, from December 2009 to October 2012. A total of 86 patients, aged 16-48 years with high Prolactinlevels, were screened with MRI for pituitary gland abnormalities. Only new undiagnosed patientswere considered for the study. Children and patients with known causes for hyperprolactinaemia wereexcluded.

Results: The most common abnormality on MRI was microadenoma (n=34, 39.5%) followed by macroadenoma(n=14, 16.3%). 12(7%) cases of complete/partial empty sella syndrome were seen. Macroadenomawas more common in males (n=6 out of 14, 42.3%) while microadenoma was more common in females(n=32 out of 72, 44.4%).

Conclusion: Majority of Patients had an abnormal MRI finding, showing that MRI screening should berecommended for Prolactin levels above 1000mIU/L. Microadenoma was the most common abnormality,having higher incidence in female patients.

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How to Cite
1.
Gul S, Naeem M, Khan MZ- ul-I, Adil M, Abbas SH, Khan A, Naz SM, Khan MU. MRI brain findings in patients with high serum prolactin levels. J Postgrad Med Inst [Internet]. 2013 Oct. 7 [cited 2022 Dec. 7];27(4). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/1410
Section
Original Article
Author Biographies

Seema Gul, Rehman Medical Institute Peshawar

Assistant Professor

Department of Radiology

Mohammad Naeem, Khyber Medical College Peshawar

Assistant Professor

Department of Community Medicine

Muhammad Zia-ul-Islam Khan, Khyber Teaching Hospital Peshawar

House Officer

Muhammad Adil, Khyber Teaching Hospital Peshawar

House Officer

Syed Hussain Abbas, Khyber Teaching Hospital Peshawar

House Officer

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