DISTRIBUTION FREQUENCY OF HEPATITIS C VIRUS GENOTYPES IN PATIENTS ATTENDING LIAQUAT UNIVERSITY HOSPITAL JAMSHORO/HYDERABAD
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Abstract
Objective: To assess the frequency of different genotypes of Hepatitis C virusin patients attending Liaquat University Hospital (LUH) Jamshoro Sindh.
Methodology: This descriptive cross sectional study was carried out at Departmentof Medicine at Liaquat University hospital Jamshoro from June to December 2012. A total of 107 patients with Hepatitis C fulfilling the selectioncriteria and with informed consent were included in the study. Blood sampleswere taken from patients for HCV genotyping. A qualified pathologist performedHCV genotyping.
Results: Total 107 patients of Hepatitis C were selected by non probabilityconsecutive sampling. Mean age was 36.58 ± 10.5 years. Fifty six (52.3%)were male and fifty one (47.7%) were female. The commonest genotype wasgenotype 3 (72.9%) followed by genotype 2 (18.7%), genotype 1 (7.5%) andgenotype 4 (0.9%). The commonest HCV genotype 3 subtype was subtype a(73.8%) followed by subtype b (25.2%) and subtype c (0.9%).
Conclusion: HCV genotype 3 with distribution frequency of 72.9% and subtypea with distribution frequency of 73.8% were the commonest in our studypopulation.
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