CRP, AN INFLAMMATORY BIOMARKER IN TYPE 2 DIABETES MELLITUS

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Sobia Ali
Mudassir Ahmad Khan
Muhmmad Ali Khan

Abstract

Objective: To find out hs-CRP levels in type 2 diabetic patients with and withoutCHD and to further evaluate association of hs-CRP with glycosylated hemoglobinand lipid profile.

Methodology: A cross- sectional / analytical study was conducted. Group Acomprised of 100 type 2 diabetic patients without CHD and Group B comprisedof 100 type 2 diabetic patients with CHD. All the patients were randomlyselected from Khyber teaching hospital (KTH) and Hyatabad MedicalComplex (HMC). Blood Glucose, Glycosylated Hemoglobin, Lipid profile andhs-CRP levels were assessed.

Results: The mean hs-CRP, FBS and glycosylated hemoglobin values were significantly(P< 0.05) high in type 2 diabetic patients having CHD than type 2diabetic patients without CHD. Moreover, hs-CRP also showed a significant(P< 0.05) positive association with FBS and HbAlc and negative associationwith HDL-C (P< 0.05).

Conclusion: It can be concluded from the study that raised levels of plasmahs-CRP in type 2 diabetic patients may contribute to ongoing atheroscleroticprocesses leading to the development of coronary heart disease in these patientsand this can be used as a marker of development of atherosclerosis inpatients with diabetes mellitus.

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How to Cite
1.
Ali S, Khan MA, Khan MA. CRP, AN INFLAMMATORY BIOMARKER IN TYPE 2 DIABETES MELLITUS. J Postgrad Med Inst [Internet]. 2015 May 12 [cited 2022 Oct. 7];29(1). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/1659
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Original Article
Author Biography

Sobia Ali

kmc, peshawar, lecturer