THE ASSOCIATION BETWEEN METABOLIC SYNDROME AND SERUM LEVELS OF MALONDIALDEHYDE AND INTERLEUKIN -6 IN GORGAN
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Published:
Jan 3, 2016
Keywords:
Metabolic Syndrome, Lipid peroxidation, Interleukin-6
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Abstract
Objective: There are limited studies on the relationship between inflamma -tory marker such as IL-6 and lipid peroxidation and metabolic syndrome. The
aim of present study was to assess IL-6 and lipid peroxidation in subjects with
and without the metabolic syndrome and their association with metabolic
syndrome components.
Methodology: Age and gender matched 40 subjects with metabolic syn -drome and 40 control groups took part in this study.
Results: The mean malondialdehyde level was significantly higher in over -weight and obese subjects with metabolic syndrome than control groups
(P<0.05). The mean level of IL-6 in men and the mean level of malondialde -hyde in women with metabolic syndrome was significantly higher than con-trol groups (p < 0.05). There were significant positive correlation between
malondialdehyde and fasting blood glucose, triglyceride and systolic blood
pressure (p<0.05).
Conclusion: Our results suggest that higher levels of IL-6 and malondialde-hyde may cause insulin resistance and metabolic disorders in all subjects with
metabolic syndrome. Malondialdehyde level shows strong association with
some metabolic syndrome components. This means the greater risk of met -abolic syndrome.
aim of present study was to assess IL-6 and lipid peroxidation in subjects with
and without the metabolic syndrome and their association with metabolic
syndrome components.
Methodology: Age and gender matched 40 subjects with metabolic syn -drome and 40 control groups took part in this study.
Results: The mean malondialdehyde level was significantly higher in over -weight and obese subjects with metabolic syndrome than control groups
(P<0.05). The mean level of IL-6 in men and the mean level of malondialde -hyde in women with metabolic syndrome was significantly higher than con-trol groups (p < 0.05). There were significant positive correlation between
malondialdehyde and fasting blood glucose, triglyceride and systolic blood
pressure (p<0.05).
Conclusion: Our results suggest that higher levels of IL-6 and malondialde-hyde may cause insulin resistance and metabolic disorders in all subjects with
metabolic syndrome. Malondialdehyde level shows strong association with
some metabolic syndrome components. This means the greater risk of met -abolic syndrome.
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How to Cite
1.
Sarbijani HM, Khoshnia M, Marjani A. THE ASSOCIATION BETWEEN METABOLIC SYNDROME AND SERUM LEVELS OF MALONDIALDEHYDE AND INTERLEUKIN -6 IN GORGAN. J Postgrad Med Inst [Internet]. 2016 Jan. 3 [cited 2024 Nov. 21];29(4). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/1763
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