FREQUENCY AND COMPLICATIONS OF ISCHEMIC MITRAL REGURGITATION IN PATIENTS WITH ACUTE CORONARY SYNDROME

Abstract

Objective: To determine the frequency of ischemic mitral regurgitation, determine
severity and defining its complications among patients with acute myocardial
infarction (MI).
Methodology: This study was conducted at Hayatabad Medical complex. Our
study was descriptive cross sectional study in which 262 patients with acute MI
were studied using non-probability consecutive sampling technique. Complications
were followed for 6 Months & recorded on a pre-designed proforma.
Results: In this study mean age was 60 ±1.26 years. One hundred and ten (42%)
patients were male while 152(58%) patients were female. One hundred thirty
six patients (52%) patients were ST elevation MI (STEMI) and 126(48%) patients
were non-ST elevation MI (NSTEMI). Mitral regurgitation was found in 141(54%)
patients in whom 104(74%) patients were found to have mild mitral regurgitation,
29(20%) patients were found to have moderate mitral regurgitation and
8(6%) patients were having severe mitral regurgitation. Moreover 25(18%) patients
had new onset atrial fibrillation, 24(17%) patients had in-hospital mortality
and 15(11%) patients were re-admission with heart failure.
Conclusion: Following myocardial infarction, baseline mitral regurgitant severity
is associated with deterioration of LV function & increased mortality. The
presence of mitral regurgitation confers poor prognosis in patients with acute
coronary syndrome.