ROLE OF VITAMIN D IN PREVENTION OF ACUTE EXACERBATION OF BRONCHIAL ASTHMA IN ADULTS

Muhammad Usman Musharraf, Ghaanfar Ali Sandhu, Muhammad Usman Mumtaz, Muhammad Farhan Rashid

Abstract


Objective: To determine role of vitamin D in prevention of acute exacerbation
of bronchial asthma in adults when added to standard treatment.
Methodology: The study included 80 patients of either gender with age ranging
from 16 to 46 years. Bronchial asthma diagnosed for at least 1 year and
vitamin D levels below 30 ng/ml, no history of smoking, intake of vitamin D 6
months before trial or other chronic diseases were included in the study. They
were randomly divided into two groups by using computer generated random
number table, group A and group B and were given combination of standard
treatment of bronchial asthma and vitamin D vs standard treatment only respectively.
Results: 25(62.5%) were male in group A while 21(52.5%) were male in group
B. Mean age of study population was 29.56 ±8.06 years. Vitamin D was found
more effective in prevention of exacerbations of bronchial asthma (P value
0.003).
Conclusion: Vitamin D was efficacious in bronchial asthma in terms of prevention
in number of exacerbations when added to standard treatment.

Keywords


Bronchial asthma, Vitamin D, Exacerbation of bronchial asthma

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