SURGICAL MANAGEMENT OF COLORECTAL CARCINOMA: CLINICAL FEATURES AND OUTCOMES AT A TERTIARY CARE HOSPITAL

Abstract

Objective: To present our experience about the surgical management and short-to-mid-term outcome of patients with colorectal cancer with an emphasis on the implications for our local population.

Methodology: This was a descriptive study conducted between July 2010 to June 2015. We included adult patients with a diagnosis of colorectal cancer who were managed surgically and they were followed-up post-operatively for up to 12 months. Patients demographics, clinical features, radiological and pathological staging, surgical intervention performed, early postoperative complications, mortality and recurrence data was obtained.

Results: A total of 81 patients were studied with a mean age of 50.25 ±4.71 years. The average follow up duration was 6.56 ±2.76 months. Among the 67 cases of adenocarcinoma, 15 (22.4%) were grade 1 tumours, 24 (35.8%) were grade 2 tumours while 28 (41.8%) were grade 3 tumours. Adenocarcinoma most frequently presented during Stage C1 (n =23, 34.3%) which was followed by 22 (32.8%) cases of stage B tumours. Squamous cell carcinoma presented during stage C2 (n =8, 57.1%) which was followed by stage C1 (n =4, 28.6%). The median survival duration during the follow-up period was 11 months (95% CI, 9.25 to 12.74).

Conclusion: Colorectal carcinoma involved younger age groups in our society with frequent late presentation. Early clinical presentation was associated with best overall and recurrence free survival while presentation at later stages of disease lead to shorter survival and early recurrence.