Evaluation of the Performance of Stone Management According to Size-Hardness (SMASH) Score in Preoperative Planning for Retrograde Internal Surgery (RIRS) in the Treatment of Renal Stones

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Assad ur Rehman
Nadeem Bin Nusrat
Shujah Muhammad
Nauman Zafar
Asadullah Aslam
Sarmad Imtiaz
Hafiz Abdul Hanan
Ammar Asghar
Sharafat Ali
Moin Arshad
Aadil Chaudhary
Saira Imtiaz

Abstract

Objectives: This study aimed to assess the effectiveness of the SMASH score in selecting candidates for Retrograde Intrarenal Surgery (RIRS).


Methodology: This retrospective study was conducted at the the Pakistan Kidney and Liver Institute and Research Center (PKLI & RC) from September 2019 to September 2024. Patients aged >14 years with renal stones sized 1–2.5 cm, undergoing their first RIRS, were included. Exclusion criteria were infected urine, staghorn stones, stones >2.5 cm, or requiring repeat intervention. The SMASH score, derived from Hounsfield units and stone size, was evaluated for its role in predicting stone clearance. Data collected included demographic, clinical, surgical, and postoperative outcomes. Statistical analysis employed Spearman's correlation and logistic regression.


Results: Among 260 patients (mean age: 44.88 ± 15.25 years), complete stone clearance was achieved in 80.4% of cases, with a higher success rate in patients with SMASH scores < 15 (67.5%, p < 0.001). Postoperative complications were seen in 12.7%, including urosepsis (9.2%) and UTIs (3.1%). Median operative and laser times were 80 minutes and 57.5 minutes, respectively, and correlated positively with SMASH scores (p = 0.194, p = 0.185, p-value < 0.01). Logistic regression identified stone size as a significant predictor of clearance (OR 5.479, p-value < 0.001). Operative time increased with stone size (p-value < 0.001), emphasizing preoperative complexity. The median hospital stay was one day, indicating rapid recovery.

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How to Cite
1.
Rehman A, Nusrat N, Muhammad S, Zafar N, Aslam A, Imtiaz S, et al. Evaluation of the Performance of Stone Management According to Size-Hardness (SMASH) Score in Preoperative Planning for Retrograde Internal Surgery (RIRS) in the Treatment of Renal Stones. J Postgrad Med Inst [Internet]. 2025 Jun. 30 [cited 2025 Jul. 9];39(2). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/3657
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Original Article

References

1. Smith LH. The medical aspects of urolithiasis: An overview. J Urol 1989;141(4):707-10.

2. Trinchieri A. Epidemiology of urolithiasis. Arch Ital Urol Androl 1996;68(3):203-49.

3. Curhan GC. Epidemiology of stone disease. Urol Clin North Am 2007;34(2):287-93.

4. Muslumanoglu AY, Binbay M, Yuruk E, Akman T, Tepeler A, Esen T, et al. Updated epidemiologic study of urolithiasis in Turkey. I: Changing characteristics of urolithiasis. Urol Res 2011;39(4):309-14.

5. Assimos D, Krambeck A, Miller NL, Monga M, Murad MH, Nelson CP, et al. Surgical management of stones: American Urological Association/Endourological Society guideline, part I. J Urol 2016;196(4):1153-60.

6. Yazici C, Akgul M, Arda E, Akpinar H. Can urologists perform stone analysis, metabolic evaluation and metaphylaxis in urinary-tract stone disease in Tekirdag? Dicle Med J 2019;46(3):405-10.

7. Perri D, Besana U, Pacchetti A, Morini E, Mazzoleni F, Calcagnile T, et al. MP29-13: Application of the stone management according to size-hardness (SMASH) score in selecting patients for retrograde intrarenal surgery. J Urol 2024;211(5S):e486. DOI: 10.1097/01.JU.0001008680.67760.37.

8. Parikh KP, Jain RJ, Kandarp AP. Is retrograde intrarenal surgery the game changer in managing upper-tract calculi? A single-center, single-surgeon experience of 131 cases. Urol Ann 2018;10(1):29-34.

9. Turk C, Petrik A, Sarica K, Seitz C, Skolarikos A, Straub M, Knoll T. EAU guidelines on interventional treatment for urolithiasis. Eur Urol 2016;69(3):475-82.

10. Al Busaidy SS, Kurukkal SN, Al Hooti QM, Alsaraf MS, Al Mamari SA, Al Saeedi AK. Is RIRS emerging as the preferred option for 2-4 cm renal stones? Our experience. Can J Urol 2016;23(5):8364-7.

11. Perri D, Besana U, Pacchetti A, Morini E, Mazzoleni F, Calcagnile T, et al. MP29-13 application of the SMASH score in selecting patients for retrograde intrarenal surgery. J Urol 2024;211(5S):e486. DOI: 10.1097/01.JU.0001008680.67760.37.

12. Perri D, Besana U, Berti L, Mazzoleni F, Pacchetti A, Morini E, et al. PD28-11: A mathematical model to plan between RIRS and miniperc for 10-20 mm renal stones using holmium:YAG laser (Cyber HO): The SMASH score. J Urol 2023;209(Suppl 4):e823. DOI: 10.1097/JU.0000000000003313.11.

13. Perri D, Besana U, Maltagliati M, Pacchetti A, Calcagnile T, Pastore AL, et al. Risk of bleeding after retrograde intrarenal surgery versus mini-PCNL for 10-20 mm renal stones: A safety profile comparison. BJU Int 2024;[epub ahead of print]. DOI: 10.1111/BJU.16585.