PROTHROMBIN TIME AS AN INDICATOR OF SEVERITY OF LIVER DISEASES
Article Sidebar
Keywords:
Prothrombin time, liver disease, indicator
Main Article Content
Abstract
Objective: To confirm that Prothrombin time is by and large the most sensitive indicator of hepatocellular function.
Material and Methods: Two hundred and twenty patients were recruited in the study from Military Hospital Rawalpindi and combined Military Hospital Peshawar over one year period 1993. All the patient went through a detailed history, hematological and screening tests. The student 't' test was used to assess the significance of results obtained.
Results: 97% of the patients were males while 69% of the total patients were in the age group of 21-30 years. 93% had viral hepatitis and out of these only 19.50% were Hbs Ag positive. The common symptoms in order of frequency were yellow sclera, loss of appetite, dark urine. Jaundice (97.2%) and palpable liver (81.36) were the most common physical signs. Patients who had PT difference less than 3 seconds from the control had mild hepatitis, while patients who had PT difference more than 3 seconds from the control, had severe hepatitis.
Conclusion: PT is a good prognostic indicator of severity of liver diseases and correlates well with the elevation of bilirubin and ALT.
Material and Methods: Two hundred and twenty patients were recruited in the study from Military Hospital Rawalpindi and combined Military Hospital Peshawar over one year period 1993. All the patient went through a detailed history, hematological and screening tests. The student 't' test was used to assess the significance of results obtained.
Results: 97% of the patients were males while 69% of the total patients were in the age group of 21-30 years. 93% had viral hepatitis and out of these only 19.50% were Hbs Ag positive. The common symptoms in order of frequency were yellow sclera, loss of appetite, dark urine. Jaundice (97.2%) and palpable liver (81.36) were the most common physical signs. Patients who had PT difference less than 3 seconds from the control had mild hepatitis, while patients who had PT difference more than 3 seconds from the control, had severe hepatitis.
Conclusion: PT is a good prognostic indicator of severity of liver diseases and correlates well with the elevation of bilirubin and ALT.
Article Details
How to Cite
1.
Niazi M. PROTHROMBIN TIME AS AN INDICATOR OF SEVERITY OF LIVER DISEASES. J Postgrad Med Inst [Internet]. 2011 Jul. 27 [cited 2024 Dec. 19];23(1). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/73
Issue
Section
Original Article
Work published in JPMI is licensed under a
Creative Commons Attribution-NonCommercial 2.0 Generic License.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.