MEDIUM TERM EFFECTIVENESS OF THYROXINE TREATMENT IN CONGESTIVE CARDIAC FAILURE (CCF)
Article Sidebar
Main Article Content
Abstract
Objective: To test the medium term efficacy of L-thyroxin compared with placebo and to find out if later effects are obtainable in patients of CCF.
Material and Methods: It was an experimental, randomized, double blind clinical trial, recruiting patients of CCF visiting O.P.D or admitted in Fauji Foundation Hospital Rawalpindi. The subjects were in two groups i.e thyroxin group (cases) and placebo group (controls) of 30 each. Pulse rate, E.C.G findings/ryhthm, cardiothoracic ratio on CXR, holter findings if applicable, ejection fraction on
echocardiography, T T T levels, weight were the parameters compared. 3 4 SH
Results: There was significant difference between the mean ejection fractions of patients with congestive cardiac failure after receiving thyroxin for 3 months. There was no significant difference between the mean ejection fractions of patients with congestive cardiac failure after receiving placebo for 3 months.
Conclusion: In heart failure a three month treatment with thyroxin has beneficial effects in terms of increasing the ejection fraction of the failing heart without inducing undesired effects like rhythm disturbances.
Material and Methods: It was an experimental, randomized, double blind clinical trial, recruiting patients of CCF visiting O.P.D or admitted in Fauji Foundation Hospital Rawalpindi. The subjects were in two groups i.e thyroxin group (cases) and placebo group (controls) of 30 each. Pulse rate, E.C.G findings/ryhthm, cardiothoracic ratio on CXR, holter findings if applicable, ejection fraction on
echocardiography, T T T levels, weight were the parameters compared. 3 4 SH
Results: There was significant difference between the mean ejection fractions of patients with congestive cardiac failure after receiving thyroxin for 3 months. There was no significant difference between the mean ejection fractions of patients with congestive cardiac failure after receiving placebo for 3 months.
Conclusion: In heart failure a three month treatment with thyroxin has beneficial effects in terms of increasing the ejection fraction of the failing heart without inducing undesired effects like rhythm disturbances.
Article Details
How to Cite
1.
Nasim A, Shahzad A, Saeed S. MEDIUM TERM EFFECTIVENESS OF THYROXINE TREATMENT IN CONGESTIVE CARDIAC FAILURE (CCF). J Postgrad Med Inst [Internet]. 2011 Jul. 28 [cited 2024 Nov. 21];23(2). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/76
Issue
Section
Original Article
Work published in JPMI is licensed under a
Creative Commons Attribution-NonCommercial 2.0 Generic License.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.