Sensititiveity patterns in Patients of Acute Secondary Bacterial Peritonitis, and Suggested Empirical Treatment

Abstract

The objective of this study was to determine the common pathogens in acute secondary bacterial peritonitis patients in tertiary care hospital and their sensitivity to the antibiotics commonly prescribed for acute bacterial peritonitits. We conducted culture sensitivity studies on 25 consecutive laparotomies for secondary peritonitis presente to our surgical A ward through accident and emergency department without any advance knowledge of thier prior antibiotic therapy or culture sensitivity of the pathogens involved. Our study revealed a very disturbing trend of occurrence of high resistance strains in patient coming directly from the communit. We suggest empirical therapies in view of our results and current medical literature. The high bacterial resistance encountered necessitates use of broad spectrum and expensive antibiotics.