PERCUTANEOUS IMAGE GUIDED CUTTING NEEDLE BIOPSY OF MEDIASTINAL MASSES: DIAGNOSTIC YIELD AND COMPLICATIONS

Abstract

Objective

:  To evaluate image guided cutting needle biopsy of mediastinal masses for diagnostic yield and complications.

Material and methods:

This was a descriptive study. Computed Tomography (CT) and ultrasound guided

biopsies of mediastinal masses were performed in 30 patients. Tissue core obtained, were preserved in

formalin and sent for histological examination. X-ray chest taken for evidence of pneumothorax and

mediastinal widening. Hemoptysis, pneumothorax other complication were recorded.

Result:

Definite histological diagnosis was obtained in all 30 patients. 70% (n=21) were malignant

disease and 30% (n=9) were benign pathologies. Sensitivity and specificity, positive and negative

predictive values were 100%. Pneumothorax occurred in 7% (n=2) cases. Hemoptysis occurred in 10%

(n=3) cases. Chest intubation was not required in cases of pneumothorax. No hemodynamic instability

occurred. There was no major complication.

Conclusion:

Image guided percutaneous transthoracic cutting needle biopsy in mediastinal masses is an

accurate procedure for specific histological diagnosis and has a low complication rate