A PROFILE OF PLASMA CONCENTRATION OF ADIPONECTIN IN PRIMARY SCHOOL CHILDREN IN DERA ISMAIL KHAN
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Abstract
Objective: The objective of the present study was to determine the plasma Adiponectin concentration in primary school children 6-11 years and to evaluatenegative association of Adiponectin in obese children.
Methodology: This cross sectional study was carried out in the Departmentof Chemistry, Gomal University, Dera Ismail Khan from June 2007 to August2010. A total number of 1336 primary school children were examined in theMunicipality area of Dera Ismail Khan and excluding those suffering fromchronic health problems. Height (m), weight (kg) of each child was taken andBMI was calculated according to Quatelet's Index. Body mass Status was alsocalculated through CDCs ׳ Growth Charts 2002, 2-20years for children to havepercentile for each school child. School children with ≥5th percentile were declarednormal weight and the ones having ≥95th percentile as obese. 83 schoolchildren were randomly selected among 1336 children with 23 (27.71%) normalweight and 60 (72.28%) as obese ones. Gender wise distribution of thesample was 48 (57.83%) boys and 35 (42.16%) as girls. Fasting plasma adiponectinconcentration was determined by ELIZA method.
Results: Mean plasma adiponectin concentration in normal weight childrenwas noted as 21.38μg/ml (P = 0.013) and 20.89μg/ml (P = 0.011) in boys andgirls respectively. The observed, mean plasma adiponectin level in obese childrenwas 20.38μg/ml (P =0.0130) and 25.56μg/ml (P = 0.0016) in boys andgirls respectively.
Conclusion: Significant difference in plasma adiponectin concentration wasobserved between normal weight and obese girls
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