PRE - TREATMENT ANXIETY AND INTERFERON INDUCED DEPRESSION IN HEPATITIS C PATIENTS
Article Sidebar
Published:
Jan 3, 2016
Keywords:
Anxiety, Interferon alpha Therapy, Depression
Main Article Content
Abstract
Objective: To study the effect of pre-treatment anxiety on interferon induced
depression in hepatitis C patients undergoing interferon treatment.
Methodology: Interrupted time series design was used for this study to as -sess at pre, in 2 follow up visits (after 24th and 48th week) and after comple -tion of the treatment. The depression and anxiety of two groups of women
(showing high and low pre-treatment anxiety score on the IPAT anxiety scale
[PTAS]) was measured by the Siddiqui Shah Depression Scale (SSDS) and the
IPAT Anxiety Scale. Female patients (n=57) being diagnosed for Hepatitis C
and prescribed for interferon therapy were selected from three main hospitals
of Peshawar, through convenience sampling technique.
Results: The age range of the sample was from 35 to 65 years (54.51+5.11
years). Compared to 25 % of the patients having low pre-treatment anxiety
scores, 32 % of the patients with higher pre-treatment anxiety score expe -rienced significant level of depression at week 24 and 48 during and after
completion of the interferon treatment.
Conclusion: Pre-treatment anxiety has significant effect on the levels of de-pression, hepatitis C patients experience during and after completion of the
treatment.
depression in hepatitis C patients undergoing interferon treatment.
Methodology: Interrupted time series design was used for this study to as -sess at pre, in 2 follow up visits (after 24th and 48th week) and after comple -tion of the treatment. The depression and anxiety of two groups of women
(showing high and low pre-treatment anxiety score on the IPAT anxiety scale
[PTAS]) was measured by the Siddiqui Shah Depression Scale (SSDS) and the
IPAT Anxiety Scale. Female patients (n=57) being diagnosed for Hepatitis C
and prescribed for interferon therapy were selected from three main hospitals
of Peshawar, through convenience sampling technique.
Results: The age range of the sample was from 35 to 65 years (54.51+5.11
years). Compared to 25 % of the patients having low pre-treatment anxiety
scores, 32 % of the patients with higher pre-treatment anxiety score expe -rienced significant level of depression at week 24 and 48 during and after
completion of the interferon treatment.
Conclusion: Pre-treatment anxiety has significant effect on the levels of de-pression, hepatitis C patients experience during and after completion of the
treatment.
Article Details
How to Cite
1.
Andleeb S, Jahangir F, Shaheen N. PRE - TREATMENT ANXIETY AND INTERFERON INDUCED DEPRESSION IN HEPATITIS C PATIENTS. J Postgrad Med Inst [Internet]. 2016 Jan. 3 [cited 2024 Nov. 21];29(4). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/1829
Issue
Section
Original Article
Work published in JPMI is licensed under a
Creative Commons Attribution-NonCommercial 2.0 Generic License.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.