PRE - TREATMENT ANXIETY AND INTERFERON INDUCED DEPRESSION IN HEPATITIS C PATIENTS
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Published:
Jan 3, 2016
Keywords:
Anxiety, Interferon alpha Therapy, Depression
Main Article Content
Abstract
Objective: To study the effect of pre-treatment anxiety on interferon induced
depression in hepatitis C patients undergoing interferon treatment.
Methodology: Interrupted time series design was used for this study to as -sess at pre, in 2 follow up visits (after 24th and 48th week) and after comple -tion of the treatment. The depression and anxiety of two groups of women
(showing high and low pre-treatment anxiety score on the IPAT anxiety scale
[PTAS]) was measured by the Siddiqui Shah Depression Scale (SSDS) and the
IPAT Anxiety Scale. Female patients (n=57) being diagnosed for Hepatitis C
and prescribed for interferon therapy were selected from three main hospitals
of Peshawar, through convenience sampling technique.
Results: The age range of the sample was from 35 to 65 years (54.51+5.11
years). Compared to 25 % of the patients having low pre-treatment anxiety
scores, 32 % of the patients with higher pre-treatment anxiety score expe -rienced significant level of depression at week 24 and 48 during and after
completion of the interferon treatment.
Conclusion: Pre-treatment anxiety has significant effect on the levels of de-pression, hepatitis C patients experience during and after completion of the
treatment.
depression in hepatitis C patients undergoing interferon treatment.
Methodology: Interrupted time series design was used for this study to as -sess at pre, in 2 follow up visits (after 24th and 48th week) and after comple -tion of the treatment. The depression and anxiety of two groups of women
(showing high and low pre-treatment anxiety score on the IPAT anxiety scale
[PTAS]) was measured by the Siddiqui Shah Depression Scale (SSDS) and the
IPAT Anxiety Scale. Female patients (n=57) being diagnosed for Hepatitis C
and prescribed for interferon therapy were selected from three main hospitals
of Peshawar, through convenience sampling technique.
Results: The age range of the sample was from 35 to 65 years (54.51+5.11
years). Compared to 25 % of the patients having low pre-treatment anxiety
scores, 32 % of the patients with higher pre-treatment anxiety score expe -rienced significant level of depression at week 24 and 48 during and after
completion of the interferon treatment.
Conclusion: Pre-treatment anxiety has significant effect on the levels of de-pression, hepatitis C patients experience during and after completion of the
treatment.
Article Details
How to Cite
1.
Andleeb S, Jahangir F, Shaheen N. PRE - TREATMENT ANXIETY AND INTERFERON INDUCED DEPRESSION IN HEPATITIS C PATIENTS. J Postgrad Med Inst [Internet]. 2016 Jan. 3 [cited 2024 Dec. 22];29(4). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/1829
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