Main Article Content
Objective: To determine level of adherence to different insulin regimens, its effect on glycemic profile and to find out reasons leading to non adherence.
Methodology: This cross sectional study was conducted at the Department of Endocrinology, Hayatabad Medical Complex, Peshawar, from February 2016 to December 2016. Two hundred patients; 148 on basal bolus and 52 on premix insulin regimen were assessed. Adherence status was determined using Morisky medication adherence scale (MMAS=0). Fasting and random glucose levels were also recorded. After stratification into different groups, chi square test was applied while mean fasting glucose levels were compared using independent samples t test.
Results: Overall adherence to insulin treatment was only 26.5%. Only 10% patients were highly adherent to treatment (MMAS=0). Only 33% patients had their fasting sugar in reasonable range (<140mg/dl). Among 148 patients on basal bolus regimen, only 15.5% were adherent to treatment while adherence to premix insulin was 57.7%. Fasting sugar levels were much better in premix group vs. basal bolus group (p value <0.05). Non-affordability was the main constraint responsible for non-adherence (54%).
Conclusion: Adherence to insulin treatment than insulin type was more important in improving diabetes care. Premix insulin was a reasonable alternative to achieve glycemic control as the cost of drug remains main reason for non adherence.
Work published in JPMI is licensed under a
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.