SIMULTANEOUS PRESENTATION OF A PATIENT WITH ACUTE CORONARY SYNDROME, ACUTE LIMB ISCHEMIA AND DEEP VENOUS THROMBOSIS COMPLICATED BY PULMONARY EMBOLISM IN EMERGENCY ROOM: A CASE REPORT

Main Article Content

Muhammad Asif Iqbal
https://orcid.org/0000-0002-3627-0198
Noor Faraz

Abstract

Deep Venous Thrombosis (DVT) develops in chronic diseases and prolonged immobilization. DVT is usually com­plicated by pulmonary embolism (PE). Common presentation of pulmonary embolism is chest pain and dyspnea. Similar is the presentation in patients with acute coronary syndrome (ACS). However, a patient who present with ACS and acute limb Ischemia and later on develop DVT complicated by PE simultaneously, is a very rare phenom­enon. Such coexistence developed by chance or a common pathophysiological process, remains unclear. Again, it is very difficult to ascertain, what was the initial event and what was the sequence of events. Management of such patients is also challenging, as priority of treatment has to be decided. ACS and acute limb ischemia, if not intervened well on time, usually end up in acute myocardial infarction or death and gangrenous limb or amputa­tion, respectively. We received a patient in emergency room with ACS, acute limb ischemia, DVT and PE. This case report was a diagnostic and management dilemma. Such a coincidence is very unusual and therefore this case is presented.

Article Details

How to Cite
1.
Iqbal MA, Faraz N. SIMULTANEOUS PRESENTATION OF A PATIENT WITH ACUTE CORONARY SYNDROME, ACUTE LIMB ISCHEMIA AND DEEP VENOUS THROMBOSIS COMPLICATED BY PULMONARY EMBOLISM IN EMERGENCY ROOM: A CASE REPORT. J Postgrad Med Inst [Internet]. 2021 Mar. 31 [cited 2024 Nov. 18];35(1):45-8. Available from: https://jpmi.org.pk/index.php/jpmi/article/view/2805
Section
Case Report

References

Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K et al. Heart disease and stroke statistics – 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Cir¬culation. 2009;119(3):480-6. https://doi. org/10.1161/circulationaha.108.191261

Lloyd-Jones DM, Hong Y, Labarthe D, Mozaffarian D, Appel LJ, Van Horn L, et al. American Heart Association Strategic Planning Task Force and Statistics Com¬mittee defining and setting national goals for cardiovascular health promotion and disease reduction: The American Heart As¬sociation’s Strategic Impact Goal Through 2020 and Beyond. Circulation. 2010; 121(4):586-613. https://doi.org/10.1161/ circulationaha.109.192703

Kones R, Phillips JH. Prevention of heart cell death. In: Yu PN, Goodwin JF, editors. Progress in cardiology. Vol. 4. Philadelphia, PA: Lea and Febiger; 1975. p.199-224.

Hyattsville, MD: National Center for Health Statistics; 2010. Health, United States, 2009: with special feature on medical technology; National Center for Health Sta¬tistics (US); 2010. Report No.: 2010-1232. p.38

Institute of Medicine (US). Committee on Public Health Priorities to Reduce and Control Hypertension in the US Population. A population-based policy and systems change approach to prevent and control hypertension. National Academies Press; 2010.

Fuster VA, Kelly BB. Institute of Medicine (US) Committee on preventing the global epidemic of cardiovascular disease: meet¬ing the challenges in developing countries. Promoting cardiovascular health in the developing world: a critical challenge to achieve global health; 2010.

Eliasson Å, Bergqvist D, Björck M, Acosta S, Sternby NH, Ögren M. Incidence and risk of venous thromboembolism in patients with verified arterial thrombosis: a popu¬lation study based on 23796 con¬secu¬tive autopsies. J Thromb Hemost. 2006; 4(9):1897-902. https://doi.org/10.1111/ j.1538-7836.2006.02152.x

Venous thromboembolism: Epidemiolo¬gy and magnitude of the problem. Best Pract Res Clin Haematol. 2012;25(3):235- 42. https://doi.org/10.1016/j. beha.2012.06.007

Reinecke H, Unrath M, Freisinger E, Bun¬zemeier H, Meyborg M, Lüders F et al. Peripheral arterial disease and critical limb ischaemia: still poor outcomes and lack of guideline adherence. Euro Heart J. 2015; 36(15):932-8. https://doi.org/10.1093/ eurheartj/2Fehv006

Goldhaber SZ, Bounameaux H. Pulmo¬nary embolism and deep vein thrombosis. The Lancet. 2012; 379(9828):1835- 46. https://doi.org/10.1016/s0140- 6736(11)61904-1

Prandoni P. Links between arterial and venous disease. J Intern Med. 2007; 262(3):341-50. https://doi.org/10.1111/ j.1365-2796.2007.01815.x

Sørensen HT, Horvath-Puho E, Lash TL, Christiansen CF, Pesavento R, Pedersen L, Baron JA et al. Heart disease may be a risk factor for pulmonary embolism without pe¬ripheral deep venous thrombo¬sis. Circu¬lation. 2011;124(13):1435-41. https://doi. org/10.1161/circulationaha.111.025627

Blaisdell FW, Steele M, Allen RE. Man¬agement of acute lower extremity arterial ischemia due to embolism and thrombosis. Surgery. 1978;84(6):822-34.

Ouriel K, Shortell CK, DeWeese JA, Green RM, Francis CW, Azodo MV, Gutierrez OH, Manzione JV, Cox C, Marder VJ. A compar¬ison of thrombolytic therapy with operative revascularization in the initial treatment of acute peripheral arterial ischemia. J Vasc Surg. 1994;19(6):1021-30. https://doi. org/10.1016/s0741-5214(94)70214-4

Jivegård L, Holm J, Schersten T. Acute limb ischemia due to arterial embolism or thrombosis: influence of limb ischemia ver¬sus pre-existing cardiac disease on post¬operative mortality rate. J Cardiovasc Surg 1988;29(1):32-6.

Rutherford RB. Clinical staging of acute limb ischemia as the basis for choice of re¬vascularization method: when and how to intervene. Semin Vasc Surg. 2009;22(1):5- 9. https://doi.org/10.1053/j.semvasc¬surg.2008.12.003

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