Main Article Content

Yasmin Akhtar
Muhammad Abdur Rahman Afridi
Zafar Ali
Atta Muhammad Khan


Objective: To determine various factors affecting adherence to antihypertensive medications.

Methodology: An observational descriptive study conducted in Medical Out-Patient Department of Lady Reading Hospital Peshawar from June 2019 to October 2019. A total of 250 adult hypertensive patients of both genders were included. Adherence to medication was assessed using ‘proportion of days covered’ method. A score of >80% was considered as ‘good adherence’. Four factors affecting adherence, were specifically studied: ‘Asymp­tomatic state’ of the patient; ‘Affordability of medications; influence of the ‘Local GP’; and ‘Adverse effects’ of the drugs. SPSS version 21 used for data analysis; correlation carried out; chi square (x2) p<0.05 considered statistically significant.

Results: Out of 250 patients, 67(26.8%) were males and 183(73.2%) females. Mean age was 56.13 years ±10.30 SD. Overall, 108(43.2%) patients had good adherence and 142(56.8%) had poor adherence (x2(4)=250.0, r(4)=0.89, p<0.001). The most common factor affecting adherence was the ‘asymptomatic’ state (56.3%, p=0.001); followed by ‘non-affordability’ (21.1%, p=0.001); ‘Local GP’ influence (14.8%, p=0.001); and drugs’ adverse effects (7.8%, p=0.003). Patients taking ‘combination’ of drugs, ARBs and BBs had 60%, 58% and 18% adherence, respectively (x2(4)=35.41, r(4)=0.50, p=0.018).

Conclusion: Factors associated with poor adherence to medications include ‘asymptomatic state’ of the patient, ‘non-affordability’ of drugs, ‘influence of local practitioner’ and ‘adverse effects’ of drugs; all significantly inversely correlated with adherence. Economic status, duration of hypertension and drug groups also significantly correlated with adherence.

Article Details

How to Cite
Yasmin Akhtar, Afridi MAR, Zafar Ali, Atta Muhammad Khan. FACTORS AFFECTING ADHERENCE TO MEDICATIONS IN HYPERTENSIVE PATIENTS VISITING A TEACHING HOSPITAL IN KHYBER PAKHTUNKHWA. J Postgrad Med Inst [Internet]. 2022 Jun. 30 [cited 2022 Aug. 19];36(2):85-90. Available from: https://jpmi.org.pk/index.php/jpmi/article/view/3060
Original Article


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