Initial Experience with I131 MIBG Imaging In Patients With Neuroblastoma
Article Sidebar
Main Article Content
Abstract
Metaiodobenzyl quanidine was synthesized from metaiodobenzyl amine hydrochloride and cyanamide at different temperatures. The yield was found to be 60-70%. The product was characterized by UV, IR, and NMR spectroscopic techniques. The characterized product was labelled with iodine -131 and labeling efficiency was determined by radio-TLC technique. Labeling yield up to 95% was achieved. Five patient with biopsy proven neuroblastoma were imaged. In two patients intrabdominal primary tumor was successfully localized and a thoracic metastatic site was detected in one of them. MIBG scanning was normal in remaining three patients.
Article Details
How to Cite
1.
Khan HA, Shah AS, Khan SM, Ahmad I, Syed GS. Initial Experience with I131 MIBG Imaging In Patients With Neuroblastoma. J Postgrad Med Inst [Internet]. 2011 Aug. 25 [cited 2024 Nov. 21];7(2). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/435
Issue
Section
Original Article
Work published in JPMI is licensed under a
Creative Commons Attribution-NonCommercial 2.0 Generic License.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.