Diagnosis of Undifferentiated Carcinoma with the Help of Monoclonal Antibodies
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Abstract
Undifferentiated carcinomas and malignancy of unknown orgin (MUO) present one of the greatest challenges to the pathologist as well as oncologist. Without knowing the primary or the type of primary tumour, it becomes very difficult for the oncologist to plan treatment for the patients. Despite exhaustive investigations, 5% of all cancer patients (and 70% of MUOs) and still have an unidentified primary tumour. due to this high rate of failure to identify the primary or the type of primary tumour, coupled with the fact that prognosis is very poor in these patients, one should only try to eliminate the most treatable tujmours (e.g. breast, ovarian, Testicular Carcinoma).
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Jameel A, Iqbal T, Khan J, Khan MA. Diagnosis of Undifferentiated Carcinoma with the Help of Monoclonal Antibodies. J Postgrad Med Inst [Internet]. 2011 Aug. 29 [cited 2024 Dec. 22];10(1). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/532
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