Effect of Ranitidine on Gastric pH and volume in women undergoing elective caesarean section

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Parhaizgar Khan
Akbar Said

Abstract

The pH and volume of the gastric fluid was analyzed using blind gastric aspiration, in 40 patients undergoing elective caesarean section. Group - I consisted of those twenty patient who received 150mg ranitidine at night and then in the morning of surgery. Group - II was given no medication. Intragastric pH and volume were measured, immediately after induction of anaesthesia and again on completion of surgery. In Group - I, the volume aspirated was 17 + 3.91 and the pH was 4.33 +1.03. In group - II the volume aspirated was 31.75 + 11.42 and the pH was 2.29 + 0.31. There is significant difference in the volume and pH of the two grups. hence this study shows that ranitidine is very effective in reducing the acidity and volume of gastric fluid in all those women undergoing elective casesarean section. 

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1.
Khan P, Said A. Effect of Ranitidine on Gastric pH and volume in women undergoing elective caesarean section. J Postgrad Med Inst [Internet]. 2011 Sep. 12 [cited 2022 Oct. 4];13(2). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/655
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