GASTRIC CARCINOMA: LOCATION, MORPHOLOGICAL AND HISTOLOGICAL PROFILE

Abstract

Objectives: To know the common tumor location, morphological and histological types of gastriccarcinoma.

Methodology: This cross sectional study was conducted in gastroenterology unit HMC from January toAugust 2010. One hundred and thirteen patients of more than 30 years of age and having endoscopic andbiopsy proven gastric carcinoma were included in the study. All patients after necessary investigation wereprepared for endoscopic examination, upper gastrointestinal endoscopy was done and findings wererecorded. Biopsies of the lesions were taken for histopathological confirmation.

Results: Seventy five (66.4%) patients were male and 38(33.6%) were female. The mean age was56.02±12.11 years. Antrum was involved in 29(25.7%) cases alone, body alone was involved in16(14.2%) cases, body and antrum in combination were involved in 15(13.3%) cases, cardia and fundus in15(13.3%) cases, cardia alone in 13(11.5%) cases, fundus alone in 6(5.3%) cases, fundus, antrum andbody in combination in 5(4.4%) cases , cardia, fundus and body in combination in 3(2.7%) cases andcardia and body in combination were involved in 2(1.8%) cases, while stomach was diffusely involved in9(8.0%) cases. Tumor was polypoid/fungating in 51(45.1%) cases, ulcerated in 43(38.1%), infiltrating in17(15.0%) and fungating and ulcerated in 2(1.8%) cases. Intestinal type gastric carcinoma was present in39(34.5%) cases and diffuse type gastric carcinoma was present in 74(65.5%) cases.

Conclusion: Gastric carcinoma is a male predominant neoplasm which commonly involves the antrum,usually as fungating or ulcerated lesion and majority of gastric carcinoma are diffused type gastriccarcinomas.