COMPARATIVE EFFECTIVENESS OF TAMSULOSIN VERSUS STANDARD MEDICAL THERAPY FOR MEDICAL MANAGEMENT OF SMALL URETERIC STONES

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Aya Khan
Tanveer Ahmad
Ismail Khan
Ikram Ullah Khattak

Abstract

 

 

Objective: To investigate and compare the effectiveness of tamsulosin versus standard medical therapy (SMT) for conservative management of ureteric stones in terms of time needed for stone expulsion, reduction in pain episodes and stone expulsion rates.

Methodology: This was a prospective non-blinded, non-randomised controlled study conducted at Urology Unit, LRH Peshawar, from July 2015 to June 2016. 50 patients were included, 25 patients in Group 1 (SMT) and 25 patients in Group 2. All patients were selected consecutively from the outpatient department with a stone size ≤10 mm. In Group 1, patients were prescribed adequate oral analgesics while Group 2 patients were given tamsulosin plus analgesics for pain relief on as need basis. Data was obtained about symptoms duration, stone size, stone location, total pain episodes and the time to passage of stone.

Results: There were 35 (70%) males and 15 (30%) females with a ratio of 2.3:1. Overall mean age was 31.84 ±5.64 years; range was 22 to 42 years; and mean duration of symptoms was 6.64 ±1.48 days. The overall mean stone size was 5.94 ±1.46 mm (range 4 mm to 9 mm). Significant differences were detected in total pain episodes (mean pain episodes for group 1= 3.64 & group 2= 1.6, p <0.0001) and stone passage time (mean passage time for group 1= 17.52 ±7.22 days & group2 = 10.44 ± 5.64 days, p <0.0001).

Conclusions: Tamsulosin effectively reduce the time needed for spontaneous expulsion of ureteric stones. It increases the rate of stone passage and importantly reduces the number of pain episodes.

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How to Cite
1.
Khan A, Ahmad T, Khan I, Khattak IU. COMPARATIVE EFFECTIVENESS OF TAMSULOSIN VERSUS STANDARD MEDICAL THERAPY FOR MEDICAL MANAGEMENT OF SMALL URETERIC STONES. J Postgrad Med Inst [Internet]. 2018 Sep. 16 [cited 2022 Aug. 20];32(3). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/2250
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Original Article
Author Biographies

Aya Khan, PG Urology Unit LRH Peshawar

PG Urology Unit LRH Peshawar

Ismail Khan, PG Urology Unit LRH Peshawar

PG Urology Unit LRH Peshawar

Ikram Ullah Khattak, PG Urology Unit LRH Peshawar

PG Urology Unit LRH Peshawar