EFFECTIVENESS OF CALCIPOTRIOL VERSUS BETAMETHASONE DIPROPIONATE IN THE TREATMENT OF MILD TO MODERATE CHRONIC PLAQUE PSORIASIS

Main Article Content

Safdar Ali
Sahibzada Mahmood Noor
Hina Zahoor
Mohammad Majid Paracha

Abstract

 

 

Objective: To compare the effectiveness of calcipotriol versus betamethasone dipropionate in the treatment of mild to moderate chronic plaque psoriasis.

Methodology: A total of 112 patients with mild to moderate psoriasis were enrolled in this randomized controlled trial. These patients were randomly allocated into two groups (A and B) by lottery method. Betamethasone dipropionate was given to group A, while calcipotriol was given to group B. Response to treatment was assessed on the basis of 50% reduction in psoriasis area and severity index (PASI) score after 4 weeks of topical treatment. SPSS version 21 for Windows was used for data entry and analysis.

Results: In group A, Betamethasosne was effective in 44 patients (78.57%), while it was not effective in 12 patients (21.43%). In group B, calcipotriol was effective in 41 patients (73.21%). while it was not effective in 15 (26.79%). The P value was 0.659 which was statistically not significant.

Conclusion: Both betamethasone dipropionate and calcipotriol were found effective in mild to moderate forms of chronic plaque psoriasis. Calcipotriol has comparable effectiveness to betamethasone dipropionate.

 

Article Details

How to Cite
1.
Ali S, Noor SM, Zahoor H, Majid Paracha M. EFFECTIVENESS OF CALCIPOTRIOL VERSUS BETAMETHASONE DIPROPIONATE IN THE TREATMENT OF MILD TO MODERATE CHRONIC PLAQUE PSORIASIS. J Postgrad Med Inst [Internet]. 2018 Nov. 28 [cited 2024 Mar. 29];32(4). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/2435
Section
Original Article
Author Biography

Sahibzada Mahmood Noor

assoc proff

Most read articles by the same author(s)