COMPARISON OF PHYTOTHERAPY WITH ALPHA ADRENOCEPTERS BLOCKERS IN THE TREATMENT OF SYMPTOMATIC BENIGN PROSTATIC HYPERPLASIA

Main Article Content

Liaqat Ali
Faiza Hayat
Samiullah Opal
Saifullah Khan
Qudratullah Khan
Kifayat Tariq

Abstract

Objective: To compare the effectiveness of alpha blocker and phytotherapy in relieving the lower urinary tract symptoms (LUTS) in patients with Benign Prostatic Hyperplasia (BPH). Methodology: This randomized controlled trial was conducted in Department of Urology, Institute of Kidney Diseases, Peshawar from June 2017 to December 2018. A total of 308 patients, divided randomly in two groups, with 154 patients in each group, were enrolled using consecutive sampling. Group A received tamsulosin (alpha blocker) while patients in group B were put on Saw Palmetto as Phytotherapy. International Prostate Symptom Score (IPSS) and Uro-flowmetry were recorded before the therapy after 1st, 2nd, 3rd and 6th months respectively. A pre-designed proforma was used to enter the data, which was analyzed on SPSS version 20.0. Descriptive and inferential statistics were calculated where needed. Results: Mean age in group A was 65.1 ± 7.09 years, while group B showed 64.7 ± 8.01 years (p=0.442). The mean of IPSS before initiation of treatment in group A was 15.3 ± 3.02 and in group B it was 16.2 ± 3.04 (p=0.07), while post treatment IPSS at 6 months, in group A mean was recorded as 8.5 ± 7.4 and in group B it was 12.07 ± 2.75 (p=0.01). In Uroflowmetry, group A showed mean pre-treatment maximum flow as 8.4 ± 1.3 and in group B it was 8.2 ± 1.1 (p=0.064), while post-treatment maximum flow at 6 months for group A showed mean of 11.8 ± 1.5 and group B had 8.2 ± 1.1 (p=0.001). Conclusion: Alpha blockers are more effective than Phytotherapy in management of symptomatic BPH. 

Article Details

How to Cite
1.
Ali L, Hayat F, Opal S, Khan S, Khan Q, Tariq K. COMPARISON OF PHYTOTHERAPY WITH ALPHA ADRENOCEPTERS BLOCKERS IN THE TREATMENT OF SYMPTOMATIC BENIGN PROSTATIC HYPERPLASIA. J Postgrad Med Inst [Internet]. 2020 Oct. 22 [cited 2023 Jun. 7];34(2). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/2707
Section
Original Article
Author Biographies

Liaqat Ali, Institute of kidney disease HMC Peshawar

Associate Professor Urology

Institute of Kidney Diseases

Faiza Hayat, Institute of Kidney Diseases

Registrar

Samiullah Opal, Institute of Kidney Diseases

Medical Officer

Saifullah Khan, Institute of Kidney Diseases

Medical Officer

Qudratullah Khan

Medical officer

Kifayat Tariq, Institute of Kidney Diseases

Medical Officer