A Study of Bronchoconstrictng Effect of Non Selective Beta Adrenergic Blocking Agent on Isolated Respiratory Smooth Muscle of Guinea-pig
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Abstract
Effect of a nonselective beta adrenergic blocking agent, propranolol, was observed on the isolated lung parenchymal strip of gunea-pig. Propranolol produced no effect on the tissue, showing that it has got no inherent kproperty of causing contraction of the tissue. Acety-choline, histamine and prostaglandin F2a produced dose related contraction of the tissue, but there was no significant change in the response of the tissue to these broncho-constricting agents in the presence of propranolol.
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Nawaz S, Ahmed AR, Ahmed QR. A Study of Bronchoconstrictng Effect of Non Selective Beta Adrenergic Blocking Agent on Isolated Respiratory Smooth Muscle of Guinea-pig. J Postgrad Med Inst [Internet]. 2011 Aug. 19 [cited 2024 Dec. 22];3(1). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/334
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