Study of the Effects of Verapamil on the Serum Glucose and Insulin Levels of Normal and Hypertensive Subjects

Abstract

the influence of verapamil on the levels of fasting serum glucose and insulin was evaluated in twenty normal subjects and thirty patients suffering from mild to moderate hypertension. The levels of glucose and insulin were determined in both the groups, before and after the oral administration of verapamil (80mg t.i.d). In normal subejcts the values of glucose and insulin were 85.0+ 9.8mg/dl and 9.8+ 4.8/u U/ml before and 84.0+ 9.5mg/dl and 9.0 + 5.3/uU/ml after adminsitration of verapamil. The differences in the control and test values were statistically not significant. it is concluded that verapamil does not produce a significant effect on the fasting serum glucose and insulin levels of both normotensive and hypertensive individuals of Pakistan population, when given in therapeutic does not for a short duration of time.