Why Are Angiotensin converting Enzyme Inhibitors Effective in Myocardial ischaemia?

Abstract

W know what we are but we know not what we may be shakespear (Ophellia, in halmet). Newer indications are being added to the condition benefiting from Angiotensin converting enzyme inhibitors. They have an extremely success ful track record for lowering systolic and diastolic blood pressure and have been employed usefully in the setting of symptomatic and asymptomatic cardiac failure and post myocardial infarction. Their new role of possessing antischaemic properties has come to limelight only recently. This article reviews the evidence and the possible mechanisms for it.