FREQUENCY OF HISTOPATHOLOGICAL PATTERNS OF RENAL DISEASES IN A TERTIARY CARE HOSPITAL

Abstract

Objective: To find out the histological patterns of renal diseases in patients,
who underwent renal biopsy at Lady Reading Hospital Peshawar, Pakistan.
Methodology: This was a descriptive study conducted at Lady Reading Hospital
Peshawar, Pakistan from July 2012 to July 2015. We performed renal biopsy of
all patients who presented with; nephrotic syndrome, non-nephrotic range significant
proteinuria, rapidly progressive glomerulonephritis, acute unexplained
renal failure, sub-acute renal failure of unknown cause and nephritic syndrome.
Results: Total number of patients were 200. Mean age was 42.5 ±8.2 yrs. In
56(28%) of the patients the histological diagnosis was focal segmental glomerulosclerosis
(FSGS), followed by membranous nephropathy (MN) 28(14%)
minimal change disease (MCD) 25(12.5%), membrano-proliferative glomerulonephritis
(MPGN) 20(10%) and lupus nephritis in 14(7%).
Conclusion: Focal segmental glomerulosclerosis was leading cause of primary
glomerular diseases. While secondary glomerular disease (SGN) in our population
was most commonly caused by lupus nephritis (LN).