THYROID DYSFUNCTION IN PATIENTS WITH TYPE 1 DIABETES: A cross-sectional study

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Gohar Khan
Tahir Ghaffar
Ibrar Ahmed
Faheem Ullah
Rabnawaz Khan
Aziz Ul Hassan Aamir

Abstract

Objective: To determine the frequency of thyroid dysfunction in patients with type 1 diabetes mellitus using thyroid function tests.

Methodology: This was a descriptive study conducted from January 2017 to June 2017. All patients presenting with type 1 diabetes mellitus (DM) were included irrespective of their age and gender. Thyroid status was determined by screening patients with thyroid stimulating hormone (TSH), free T4 (FT4) and free T3 (FT3). Patients were categorised into five groups consisting of euthyroid, subclinical/overt hypothyroidism and subclinical/overt hyperthyroidism.

Results: One hundred and four patients comprising of 38 (36.5%) males and 66 (63.5%) females had an overall mean age of 20.5 ±4.4 years, mean body mass index (BMI) 24.9 ±1.6 and mean duration of diabetes of 3.7 ±1.4 years. The mean HBA1c was 7.9 ±0.71% and mean TSH was 5.4 ±4.4 m IU/mL. Twelve (11.5%) patients were hypothyroid, 16 (15.4%) had subclinical hypothyroidism and 76 (73.1%) were euthyroid. No case of hyperthyroidism was seen.

Conclusion: Thyroid dysfunction especially overt and subclinical hypothyroidism were commonly found in patients with type 1 diabetes mellitus.

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How to Cite
1.
Khan G, Ghaffar T, Ahmed I, Ullah F, Khan R, Aamir AUH. THYROID DYSFUNCTION IN PATIENTS WITH TYPE 1 DIABETES: A cross-sectional study. J Postgrad Med Inst [Internet]. 2019 Oct. 10 [cited 2021 Sep. 25];33(2). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/2315
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Original Article
Author Biographies

Tahir Ghaffar

ASSISTANT PROFESSOR, Endocrinology LRH Peshawar

Ibrar Ahmed

Department of Endocrinology and Diabetes ,HMC Peshawar

Faheem Ullah

Department of Endocrinology and Diabetes ,HMC Peshawar

Rabnawaz Khan

Department of Endocrinology and Diabetes ,HMC Peshawar

Aziz Ul Hassan Aamir

Department of Endocrinology and Diabetes ,HMC Peshawar

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