Peflacin (Pefloxacin) in the treatment of Typhoid Fever
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Abstract
Twenty Five patients (mean age of 23.9 years) with clinical diagnosis of typhoid fever supported with positive widal test and / or blood / bone marrow culture were included in the trial. Most of the patient had already used Chloramphenicol and Amoxycillin without any effect. Peflacin (Pefloxacin) was administered orally to all patients at a daily dose of 800mg (400 mg B.D) for seven days. Clinical cure was achieved in all patients and 90% of them were apyrexial on the 4th day of treatment. They remained apyrexial for 4 weeks after completion of treatment. Patient compliance was god and well tolerated the drug.
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Saeedi MI, Khan MA, Shah SM, Rehman M ur, Ahmad M, Zubair T. Peflacin (Pefloxacin) in the treatment of Typhoid Fever. J Postgrad Med Inst [Internet]. 2011 Aug. 28 [cited 2024 Dec. 19];9(1). Available from: https://jpmi.org.pk/index.php/jpmi/article/view/487
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