Freshely prepared Rapid Urease Test Solution the Most Suitable test for Hellicobacter pylori Detection in our setup

Abstract

Rapid urease test is a common diagnostic modality for the detection of helicobacter pylori. Despite the availabiity of many commercial rapid urease test preparations in the market, physicians face difficulty in accessing these due to various factors. We therefore, have adapted to the method of preparing a fresh urease solution in our laboratory from the locally available ingredients. This dolution was then compared to a commercial rapid urease preparation and histology for the detection of helicobacter pylori in the gastric biopsy specimens of the dyspeptic patients undergoing a diagnostic upper GI endoscopyp. The solution waws found to the simple to prepare, extremely cheap (2.98Rs), and of high sensitivity (92.3%) and specificity (100%). We encourage the use of this solution on local level to help fight against this important organism.