MAGNESIUM SULPHATE THERAPY IN ECLAMPSIA: A 5 YEARS EXPERIENCE AT A TEACHING HOSPITAL
Main Article Content
: To describe the presentation of eclampsia, its management and associated outcomes using
This descriptive study was conducted at Obstetrics and Gynecology unit, Hayatabad Medical
Complex, Peshawar from January 2004 to December 2008. Data was collected from all patients presenting
: A total of 146 patients had eclampsia. Unbooked were 124 (84.93%). Mean age 23 years ± 5.3
years (range 18-38 years), primigravida were 69.17 %(101 cases). Antepartum fits in 72.6 % (106 cases),
intrapartum 14 (9.58%) and 27(18.49%) postpartum. MgSO4 was used in all except 4 with oliguria, they
were given diazepam. Recurrent fit occurred in only 20(13.69%). MgSO4 toxicity occurred as respiratory
depression in 9 cases., depressed tendon reflexes in 10 and decreased urine output in 13 cases Total
deliveries were 23021, prevalence of eclampsia was 0.63% .Mode of delivery was Vaginal in 97 (66.43%),
instrumental in 29 (19.98%) and cesarean section in 20 (13.69%)cases. There were 26(17.2%) stillbirths
and 4 neonatal deaths. Complications included HELLP in 17 (11.64%), pulmonary complications in 17,
renal failure in 7(4.79%), DIC in 16(10.95%) and temporary blindness in 16 cases. Eleven (7.53%)
maternal deaths occurred, causes included DIC in 1case, HELLP in 2, renal failure 1, cardiopulmonary
failure in 2 and CVA (recieved deeply unconscious) in 5 cases. All were unbooked cases and with delay in
Eclampsia is common antenatally and in primigravidae, and a major cause of maternal
morbidity and mortality in our region.It was effectively controlled with MgSO4, preventing recurrent fits
and safe for both mother and fetus.
magnesium sulphate (MgSO4), over a five years period at a tertiary care hospital.
Work published in JPMI is licensed under a
Creative Commons Attribution-NonCommercial 2.0 Generic License.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.